Vitamin B12 supplementation in untreatable hiccup – case study

Marek Stefan Rogoziński

doi:10.5114/pm.2022.127043

eISSN: 2081-2833
ISSN: 2081-0016

Medycyna Paliatywna/Palliative Medicine

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4/2022
vol. 14

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abstract:

Case report

Vitamin B12 supplementation in untreatable hiccup – case study

Marek Stefan Rogoziński

¹

Klinika Medycyny Paliatywnej, USK im. WAM – CSW w Łodzi, Łódź, Polska

Medycyna Paliatywna 2022; 14(4): 197–200

DOI: https://doi.org/10.5114/pm.2022.127043

Online publish date: 2023/04/28

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Hiccup is a common symptom among palliative patients. However, its pathomechanism remains little known, which makes effective treatment difficult. The following article presents a patient case study after treatment for gastric adenocarcinoma, in whom untreatable hiccup developed. After exclusion of the most common causes of singultus, attention was drawn to deepening vitamin B12, deficiency – macrocytic anaemia. As a result of substitution treatment, there has been a permanent cessation of the ailments. This case suggests that cobalamin can be one of the alternative methods in hiccup management, which would demand further research.

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Vitamin B12 supplementation in untreatable hiccup – case study

Marek Stefan Rogoziński 1

hiccups, vitamin B12, homocysteine, methylmalonic acid

Marek Stefan Rogoziński

¹