1. Coulie P, Van den Eynde B, van der Bruggen P, Boon T (2014): Tumour antigens recognized by T lymphocytes: at the core of cancer immunotherapy. Nat Rev Cancer 14: 135-146.
2.
Velardi E, Tsai J, van den Brink M (2021): T cell regeneration after immunological injury. Nat Rev Immunol 21: 277-291.
3.
Gaud G, Lesourne R, Love P (2018): Regulatory mechanisms in T cell receptor signalling. Nat Rev Immunol 18: 485-497.
4.
Hosokawa H, Rothenberg E (2021): How transcription factors drive choice of the T cell fate. Nat Rev Immunol 21: 162-176.
5.
von Meyenn L, Bertschi N, Schlapbach C (2019): Targeting T cell metabolism in inflammatory skin disease. Front Immunol 10: 2285.
6.
Mateo J, García-Lecea M, Cadenas S, et al. (2003): Regulation of hypoxia-inducible factor-1alpha by nitric oxide through mitochondria-dependent and -independent pathways. Biochem J 376: 537-544.
7.
Hu C, Xuan Y, Zhang X, et al. (2022): Immune cell metabolism and metabolic reprogramming. Mol Biol Rep 49: 9783-9795.
8.
Chakraborty S, Khamaru P, Bhattacharyya A (2022): Regulation of immune cell metabolism in health and disease: special focus on T and B cell subsets. Cell Biol Int 46: 1729-1746.
9.
Huang J, Li Z, Hu Y, et al. (2022): Melatonin, an endogenous hormone, modulates Th17 cells via the reactive-oxygen species/TXNIP/HIF-1α axis to alleviate autoimmune uveitis. J Neuroinflammation 19: 124.
10.
Kouakanou L, Xu Y, Peters C, et al. (2020): Vitamin C promotes the proliferation and effector functions of human γδ T cells. Cell Mol Immunol 17: 462-473.
11.
Johnson MO, Siska PJ, Contreras DC, Rathmell JC (2016): Nutrients and the microenvironment to feed a T cell army. Semin Immunol 28: 505-513.
12.
Maciolek JA, Pasternak JA, Wilson HL (2014): Metabolism of activated T lymphocytes. Curr Opin Immunol 27: 60-74.
13.
Buck MD, O’Sullivan D, Pearce EL (2015): T cell metabolism drives immunity. J Exp Med 212: 1345-1360.
14.
Jiao B, Liu S, Zhao H, et al. (2022): Hypoxia-responsive circRNAs: A novel but important participant in non-coding RNAs ushered toward tumor hypoxia. Cell Death Dis 13: 666.
15.
Mortezaee K, Majidpoor J (2021): The impact of hypoxia on immune state in cancer. Life Sci 286: 120057.
16.
Hu J, Li X, Yang L, Li H (2022): Hypoxia, a key factor in the immune microenvironment. Biomed Pharmacother 151: 113068.
17.
Xu L, Ma Q, Zhu J, et al. (2018): Combined inhibition of JAK1,2/Stat3 PD L1 signaling pathway suppresses the immune escape of castration resistant prostate cancer to NK cells in hypoxia. Mol Med Rep 17: 8111-8120.
18.
You L, Wu W, Wang X, et al. (2021): The role of hypoxia- inducible factor 1 in tumor immune evasion. Med Res Rev 41: 1622-1643.
19.
Nguyen HD, Kuril S, Bastian D, Yu XZ (2018): T-cell metabolism in hematopoietic cell transplantation. Front Immunol 9: 176.
20.
Sun L, Fu J, Zhou Y (2017): Metabolism controls the balance of Th17/T-regulatory cells. Front Immunol 8: 1632.
21.
Jung J, Zeng H, Horng T (2019): Metabolism as a guiding force for immunity. Nat Cell Biol 21: 85-93.
22.
Wang Y, Qin L, Chen W, et al. (2021): Novel strategies to improve tumour therapy by targeting the proteins MCT1, MCT4 and LAT1. Eur J Med Chem 226: 113806.
23.
Silva A, Antunes B, Batista A, et al. (2021): In vivo anticancer activity of AZD3965: A systematic review. Molecules 27: 181.
24.
Al Tameemi W, Dale TP, Al-Jumaily RMK, Forsyth NR (2019): Hypoxia-modified cancer cell metabolism. Front Cell Dev Biol 7: 4.
25.
Halford S, Veal GJ, Wedge SR, et al. (2023): A phase I dose-escalation study of AZD3965, an oral monocarboxylate transporter 1 inhibitor, in patients with advanced cancer. Clin Cancer Res 29: 1429-1439.
26.
Roy S, Rizvi Z, Awasthi A (2018): Metabolic checkpoints in differentiation of helper T cells in tissue inflammation. Front Immunol 9: 3036.
27.
Bao M, Wong C (2021): Hypoxia, metabolic reprogramming, and drug resistance in liver cancer. Cells 10: 1715.
28.
Chihanga T, Vicente-Muñoz S, Ruiz-Torres S, et al. (2022): Head and neck cancer susceptibility and metabolism in Fanconi anemia. Cancers 14: 2040.
29.
Santos S, Lira F, Silva E, et al. (2019): Effect of moderate exercise under hypoxia on Th1/Th2 cytokine balance. Clin Respir J 13: 583-589.
30.
Li Y, Wang Y, Shi F, et al. (2022): Phospholipid metabolites of the gut microbiota promote hypoxia-induced intestinal injury via CD1d-dependent γδ T cells. Gut Microbes 14: 2096994.
31.
Liu J, Zhang X, Chen K, et al. (2019): CCR7 chemokine receptor-inducible lnc-Dpf3 restrains dendritic cell migration by inhibiting HIF-1α-mediated glycolysis. Immunity 50: 600-615.e615.
32.
Moura C, Lollo P, Morato P, Amaya-Farfan J (2018): Dietary nutrients and bioactive substances modulate heat shock protein (HSP) expression: a review. Nutrients 10: 683.
33.
Ban H, Han T, Hur K, Cho H (2019): Epigenetic alterations of heat shock proteins (HSPs) in cancer. Int J Mol Sci 20: 4758.
34.
Agarwal S, Ganesh S (2020): Perinuclear mitochondrial clustering, increased ROS levels, and HIF1 are required for the activation of HSF1 by heat stress. J Cell Sci 133: jcs245589.
35.
Ahn J, Zhou X, Dowd S, et al. (2013): Insight into hypoxia tolerance in cowpea bruchid: metabolic repression and heat shock protein regulation via hypoxia-inducible factor 1. PLoS One 8: e57267.
36.
Pathria G, Scott DA, Feng Y, et al. (2018): Targeting the Warburg effect via LDHA inhibition engages ATF4 signaling for cancer cell survival. EMBO J 37: e99735.
37.
Sleiman S, Marshall AE, Dong X, et al. (2022): Compound heterozygous variants in SHQ1 are associated with a spectrum of neurological features, including early-onset dystonia. Hum Mol Genet 31: 614-624.
38.
Joshi A, Thinakaran G, Elferink C (2022): Cinnabarinic acid- induced stanniocalcin 2 confers cytoprotection against alcohol-induced liver injury. J Pharmacol Exp Ther 381: 1-11.
39.
Li Q, Zhou X, Fang Z, Pan Z (2019): Effect of STC2 gene silencing on colorectal cancer cells. Mol Med Rep 20: 977-984.
40.
Rabinovich S, Adler L, Yizhak K, et al. (2015): Diversion of aspartate in ASS1-deficient tumours fosters de novo pyrimidine synthesis. Nature 527: 379-383.
41.
Somanath P, Chen J, Byzova T (2008): Akt1 is necessary for the vascular maturation and angiogenesis during cutaneous wound healing. Angiogenesis 11: 277-288.
42.
Huang W, Qian T, Cheng Z, et al. (2020): Prognostic significance of Spinster homolog gene family in acute myeloid leukemia. J Cancer 11: 4581-4588.
43.
Ersahin T, Tuncbag N, Cetin-Atalay R (2015): The PI3K/AKT/mTOR interactive pathway. Mol Biosyst 11: 1946-1954.
44.
Xia P, Xu XY (2015): PI3K/Akt/mTOR signaling pathway in cancer stem cells: from basic research to clinical application. Am J Cancer Res 5: 1602-1609.
45.
Vrtačnik P, Ostanek B, Mencej-Bedrač S, Marc J (2014): The many faces of estrogen signaling. Biochem Medica 24: 329-342.
46.
Mohammad I, Starskaia I, Nagy T, et al. (2018): Estrogen receptor α contributes to T cell-mediated autoimmune inflammation by promoting T cell activation and proliferation. Sci Signal 11: eaap9415.
47.
Abraham RT, Weiss A (2004): Jurkat T cells and development of the T-cell receptor signalling paradigm. Nat Rev Immunol 4: 301-308.
48.
Murray CM, Hutchinson R, Bantick JR, et al. (2005): Monocarboxylate transporter MCT1 is a target for immunosuppression. Nat Chem Biol 1: 371-376.
