eISSN: 1897-4252
ISSN: 1731-5530
Kardiochirurgia i Torakochirurgia Polska/Polish Journal of Thoracic and Cardiovascular Surgery
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SCImago Journal & Country Rank
4/2021
vol. 18
 
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abstract:
Original paper

Mean platelet volume as a simple marker of repeated coronary artery intervention after off-pump technique (OPCAB) procedures – initial report

Tomasz K. Urbanowicz
1
,
Michał Michalak
2
,
Weronika Mikołajewska
3
,
Michał Rodzki
1
,
Bartłomiej Perek
1
,
Anna Olasińska-Wiśniewska
1
,
Michał Bociański
1
,
Marek Jemielity
1

  1. Cardiac Surgery and Transplantology Department, Poznan University of Medical Sciences, Poznan, Poland
  2. Department of Computer Science and Statistics, Poznan University of Medical Sciences, Poznan, Poland
  3. Poznan University of Medical Sciences, Poznan, Poland
Kardiochirurgia i Torakochirurgia Polska 2021; 18 (4): 231-235
Online publish date: 2022/01/09
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Introduction
Mean platelet volume (MPV) is claimed to be a useful marker to predict long-term risk for major adverse cardiac effects (MACE) in patients undergoing percutaneous coronary interventions (PCI).

Aim
To explore the possible dependence on MPV and postoperative PCI risk in patients with complex coronary artery disease undergoing coronary artery bypass grafting in off-pump technique (OPCAB).

Material and methods
We retrospectively analyzed 236 consecutive patients (180 (76%) males and 56 (24%) women) referred for surgery due to complex coronary artery disease between 2015 and 2016 in our department. The mean 5.1 ±0.8 year follow-up included profound analysis of MACE events including acute coronary syndromes and percutaneous interventions.

Results
The 5 ±1 year follow-up was completed by 213 (90%) patients with 2 (1%) deaths within the first year after surgery. In logistic univariate and multivariate model regression analysis two parameters were found significant, i.e. preoperative white blood cells and postoperative MVP, for PCI risk in long-term follow-up. The odds ratio values for postoperative MPV were 1.78 (95% CI, p = 0.0036) and 1.76 (95% CI, p = 0.005) in univariate and multivariate models with cutoff point > 8.7, sensitivity 45.65%, specificity 78.72%.

Conclusions
MPV can be regarded as a simple marker of PCI risk following OPCAB procedures. The preoperative MPV indicates the individual tendency for worse prognosis more than procedure dependence.

keywords:

off-pump coronary artery bypass, mean platelet volume, major adverse cardiac events, white blood cells

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