eISSN: 2299-0046
ISSN: 1642-395X
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
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4/2024
vol. 41
 
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abstract:
Review paper

Hidradenitis suppurativa: a new therapeutic approach for an old disease

Marta Billewicz
1
,
Joanna Wojtania
1
,
Anna Woźniacka
1

  1. Department of Dermatology and Venereology, Medical University of Lodz, Lodz, Poland
Adv Dermatol Allergol 2024; XLI (4): 350-356
Online publish date: 2024/08/12
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Hidradenitis suppurativa (HS) is a chronic inflammatory disease characterised by recurrent painful nodules, abscesses, fistulas and scarring. The primary distinguishing factor in the complex, yet still not fully understood, pathogenesis is an inflammation occurring within the hair follicle, followed by an immune response leading to further development of the skin lesions seen in HS. The treatment of patients with HS is very difficult due to the complexity of the lesions and the frequent tendency to recurrence, which also has a negative impact on the psychological state of patients and directly translates into a reduced quality of life. This review article addresses the pathogenesis, clinical presentation of HS and, in particular, explores the new therapeutic options available.
keywords:

hidradenitis suppurativa, acne inversa, biologic therapy, JAK inhibitors

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