Exploring the role of hyperforin in modulating the NF-κB/miR-21 axis  in sepsis-induced acute kidney injury

Paulina Niedźwiedzka-Rystwej; Dorota Siwicka; Andrzej Eljaszewicz

doi:10.5114/ceji.2024.142413

eISSN: 1644-4124
ISSN: 1426-3912

Central European Journal of Immunology

Current issue Archive Manuscripts accepted About the journal Special Issues Editorial board Abstracting and indexing Subscription Contact Instructions for authors Publication charge Ethical standards and procedures

Editorial System

Submit your Manuscript

2/2024
vol. 49

Send email

Copy url:

Editor’s Pick

Exploring the role of hyperforin in modulating the NF-κB/miR-21 axis in sepsis-induced acute kidney injury

Paulina Niedźwiedzka-Rystwej

^{1, 2}

,

Dorota Siwicka

³

,

Andrzej Eljaszewicz

⁴

Institute of Biology, University of Szczecin, Szczecin, Poland
Centre for Experimental Immunology and Immunobiology in Infectious Disease and Cancer, University of Szczecin, Szczecin, Poland
Department of Anaesthesiology and Intensive Care, Medical University in Lublin, Lublin, Poland
Centre of Regenerative Medicine, Medical University of Bialystok, Bialystok, Poland

Cent Eur J Immunol 2024; 49 (2): 91

DOI: https://doi.org/10.5114/ceji.2024.142413

Online publish date: 2024/08/26

Article file

- Exploring the role of hyperforin.pdf [0.09 MB]

Get citation

PlumX metrics:

1. KDIGO AKI Work Group (2012): KDIGO clinical practice guideline for acute kidney injury. Kidney Int Suppl 2: 1-138.

2. Kellum JA, Romagnani P, Ashuntantang G, et al. (2021): Acute kidney injury. Nat Rev Dis Primers 7: 52.

3. Jiang W, Song L, Zhang Y, et al. (2024): The influence of gender on the epidemiology of and outcome from sepsis associated acute kidney injury in ICU: a retrospective propensity-matched cohort study. Eur J Med Res 17: 29-56.

4. Hoste EA, Bagshaw SM, Bellomo R, et al. (2015): Epidemiology of acute kidney injury in critically ill patients: the multinational AKI-EPI study. Intensive Care Med 41: 1411-1423.

5. Kellum JA, Lameire N, KDIGO AKI Guideline Work Group (2013): Diagnosis, evaluation, and management of acute kidney injury: a KDIGO summary (Part 1). Crit Care (London, England) 17: 204.

6. Fan H, He X, Tong H, Chen K (2024): Preventive effect of hyperforin on lipopolysaccharide-induced acute kidney injury and inflammation by repressing the NF-κB/miR-21 axis. Cent Eur J Immunol 49: 169-186.

7. Novelli M, Beffy P, Menegazzi M, et al. (2014): St. John’s wort extract and hyperforin protect rat and human pancreatic islets against cytokine toxicity. Acta Diabetol 51: 113-121.

8. Chen WT, Chen YK, Lin SS, Hsu FT (2018): Hyperforin suppresses tumor growth and NF-κB-mediated anti-apoptotic and invasive potential of non-small cell lung cancer. Anticancer Res 38: 2161-2167.

9. Novelli M, Menegazzi M, Beffy P, et al. (2016): St. John’s wort extract and hyperforin inhibit multiple phosphorylation steps of cytokine signaling and prevent inflammatory and apoptotic gene induction in pancreatic β cells. Int J Biochem Cell Biol 81: 92-104.

10. Li XX, Yan Y, Zhang J, et al. (2023): Hyperforin: A natural lead compound with multiple pharmacological activities. Phytochemistry 206: 113526.

11. Wang B, Wang Y, Xu K, et al. (2021): Resveratrol alleviates sepsis-induced acute kidney injury by deactivating the lncRNA MALAT1/MiR-205 axis. Cent Eur J Immunol 46: 295-304.

12. Zhou Y, Wang Y, Li Q, et al. (2022): Downregulation of lnc-RNA NEAT1 alleviates sepsis-induced acute kidney injury. Cent Eur J Immunol 47: 8-19.

13. Pickkers P, Angus DC, Bass K, et al. (2024): Phase-3 trial of recombinant human alkaline phosphatase for patients with sepsis-associated acute kidney injury (REVIVAL). Intensive Care Med 50: 68-78.

Copyright: © 2024 Polish Society of Experimental and Clinical Immunology This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License (http://creativecommons.org/licenses/by-nc-sa/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.

Exploring the role of hyperforin in modulating the NF-κB/miR-21 axis in sepsis-induced acute kidney injury

Paulina Niedźwiedzka-Rystwej 1, 2 , Dorota Siwicka 3 , Andrzej Eljaszewicz 4

Paulina Niedźwiedzka-Rystwej

^{1, 2}

,

Dorota Siwicka

³

,

Andrzej Eljaszewicz

⁴