eISSN: 1644-4124
ISSN: 1426-3912
Central European Journal of Immunology
Current issue Archive Manuscripts accepted About the journal Special Issues Editorial board Abstracting and indexing Subscription Contact Instructions for authors Publication charge Ethical standards and procedures
Editorial System
Submit your Manuscript
SCImago Journal & Country Rank
4/2017
vol. 42
 
Share:
Share:
abstract:
Clinical immunology

Concentration of MMP-8 and IL-1β in gingival crevicular fluid in patients with chronic and aggressive periodontitis

Małgorzata Nędzi-Góra
,
Renata Górska
,
Jolanta Kostrzewa-Janicka
,
Jan Kowalski

(Centr Eur J Immunol 2017; 42 (4): 342-346)
Online publish date: 2017/12/30
View full text Get citation
 
PlumX metrics:
Modern research confirms the role of inflammatory mediators in the pathomechanism of perio­dontal tissue destruction. The aim of the study was to determine concentrations of MMP-8 and IL-1βin gingival crevicular fluid (GCF) in patients with advanced chronic and aggressive periodontitis. The authors measured the concentrations of the above inflammatory mediators in gingival crevicular fluid of deep pockets (PD ≥ 6 mm) and shallow pockets (PD 4-5 mm) in 33 patients with advanced chronic periodontitis and in 16 patients with aggressive periodontitis. The control group consisted of 16 individuals with healthy periodontium. In all patients levels of MMP-8 and IL-1β in GCF were determined with the ELISA method. The study showed significantly higher concentrations of MMP-8 and IL-1β

in GCF of both deep and shallow pockets in patients with periodontitis compared to healthy subjects. No difference in concentrations of the tested mediators was observed with reference to diagnosis of aggressive periodontitis (AP) or chronic periodontitis (CP).
keywords:

periodontitis, markers, gingival crevicular fluid

Quick links
© 2024 Termedia Sp. z o.o.
Developed by Bentus.